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高巍
来源:研究生招生网 作者:研究生招生网 点击数: 发表时间:2025-03-27 14:02:23
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个人简介:

高巍,女,1983124日出生,博士学历学位,副主任医师、副研究员,陕西中医药大学研究生指导教师。现任西安交通大学第一附属医院麻醉手术部总院科研副主任、东院区麻醉手术部主任。任国家自然科学基金和省基金评审人、中华医学会麻醉学分会青委、中国中医药信息学会科创分会和外科分会第一届理事、陕西省医学会麻醉学分会第九届委员会青委副主任委员、第五届陕西省青年科技工作者协会个人会员、中华医学会口腔镇痛镇静分会青年委员、西安医学会麻醉学分会常委兼秘书等学术任职。

学习工作经历:

20067月本科毕业于山西医科大学临床专业2009年7月硕士毕业于第四军医大学麻醉学专业2012年12月博士毕业于西安交通大学生物医学工程专业2013年1月西安交通大学第一附属医院工作,主要从事临床麻醉、科研、教学、管理工作122019年获得陕西省青年科技新星2020年获得陕西省青年拔尖人才2019年在总院开设了门诊舒适化支气管镜诊疗业务,2023年在东院开设了麻醉睡眠业务,2024年发表临床研究被国际指南收录由于业务能力突出,2021年成为西安交通大学第一附属医院第一批年轻干部,且是唯一双挂职考察干部,担任东院麻醉手术部临时负责人和总院转化医学中心副主任,表现优异,2022年7月正式聘任为总院科研副主任、东院区麻醉手术部主任。

研究方向:

麻醉药物纳米载体的基础研究、麻醉术后并发症防治的临床研究科研课题:

1)国家重点研发计划重点专项课题“常见多发病防治研究”重点专项围手术期心脑血管事件风险智能化控制技术与麻醉机器人研发(2023YFC2506900)子课题智能化控制技术与麻醉机器人的临床验证及推广应用(2023YFC2506905),155万2024.01-2028.12,在研,主持

2)陕西省“高层次人才特殊支持计划”青年 拔尖人才,100万在研,主持

3)缺血脑区靶向纳米线粒体治疗脑卒中的作用及机制研究,国家自然科学基金面上项目(NO.81971290),2020.01-2023.12,55万已结题,主持

4)磷脂酰纳米螺旋载体HSBH2D介导γ-GSH高效镇静苏醒及脑靶向二级递送机制研究,国家自然科学基金面上项目(NO.81771485), 2018.1-2021.12,54万已结题,主持

5)脑靶向有机控释丙泊酚-丙酸酯直链淀粉纳米螺旋系统的研究,国家自然科学基金青年科学基金项目资助 (NO. 81301308), 2014.01-2016.12.,23万已结题,主持

6)缺血脑区靶向纳米线粒体治疗脑卒中的作用及机制研究,一般项目-社会发展领域(2020SF-136),2020.01-2021.12,8万已结题,主持

7)脑靶向油相控释丙泊酚纳米螺旋载体的制备及机理研究,陕西省自然科学基础研究青年人才项目资助 (NO. 2014JQ4158), 2014.05-2016.4, 2万已结题,主持

8UGECLIA法检测血清UCHL1、GFAP预测术后脑卒中,2019, 省级创新人才推进计划-青年科技新星项目(2019KJXX-046),2019.6.1-2021.5.31,10万已结题,主持

发表论文:

1Shuo Zhang, Yishu Wang, Mingting Zhu, Bingyang Liu, Wenpu Zhao, Shuai Zhang, Ji Xia, Lei Shi, Peng Tang, Feiqian Wang, Siyuan Zhang, Mingxi Wan, Daocheng Wu*,Wei Gao*,Ultrasound combined blood-brain barrier targeting brain delivery of four-in-one molecular aggregates for the enhancement of anesthetic efficacy and toxicity reduction via propofol-etomidate synergistically inhibition GABA receptor. Aggregate. 2024;5:e573. (IF 13.9, Q1)

2Wei Gao#, Yongchun Liu#, Guixia Jing, Ke Li, Yuan Zhao, Baoyong Sha*,Qiang Wang*, Daocheng Wu*. Rapid and efficient crossing blood-brain barrier: Hydrophobic drug delivery system based on propionylated amylose helix nanoclusters. Biomaterials, 2017, 113: 133-144. (IF 15.304, Q1)

3Wei Gao#, Baoyong Sha#, Wei Zou, Xuan Liang, XiangzhongMeng, HaoXu, Jun Tang, Daocheng Wu*, LixianXu*, Hui Zhang*. Cationic Amylose-Encapsulated Bovine Hemoglobin as a Nanosized Oxygen Carrier. Biomaterials, 2011, 32(35): 9425–9433. (IF 15.304, Q1)

4Ya Wang, Yujie Zhang, Xiaojiang Zhang, Zhe Zhang, Junjun She, Daocheng Wu*,Wei Gao*. High Drug-Loading Nanomedicines for Tumor Chemo–Photo Combination Therapy: Advances and Perspectives. Pharmaceutics, 2022, 14, 1735. (IF 6.525, Q1)

5Shuo Zhang, Shuai Zhang, Siyuan Luo, Peng Tang, Mingxi Wan, Daocheng Wu*, Wei Gao*. Ultrasound-assisted brain delivery of nanomedicines for brain tumor therapy: advance and prospect. Journal of Nanobiotechnology, 2022, 20(1), 287. (IF 9.429, Q1)

6Guozun He, Ning Bu,Ya Juan Li,Yuan Gao, Ge Wang, Zhidong Kong, Min Zhao,Shanshan Zhang,Wei Gao*. Extra loading dose of dexmedetomidine enhances intestinal function recovery after colorectal resection: A retrospective cohort study. Frontiers in Pharmacology, 2022,13:(1-10). (IF 5.988, Q1)

7Wei Gao, Wanpeng Li, Yuqiang Yan, Rui Yang, Yuqin Zhang, Meisheng Jin, Zhikai Luo, Li Xie, Yulin Ma, Xitong Xu, Ge Wang, Zhidong Kong, Yuan Gao, Yajuan Li, Zhen Ruan, Jie Zheng, Daqing Ma*, Qiang Wang*. Transcutaneous electrical acupoint stimulation applied in lower limbs decreases the incidence of paralytic ileus after colorectal surgery: A multicenter randomized controlled trial. Surgery, 2021, Sep 05:(1-9). (IF 4.348, Q1)

8Wei Gao, Jun Li, Christine Nguyen-Buckley, Jennifer NguyenLee, Christopher Wray, Vatche Agopian, Ronald W. Busuttil, Randolph H. Steadman, Victor W. Xia*. Intraoperative hypertension and thrombocytopenia associated with intracranialhemorrhage after liver transplantation. Transplantation 2020, 104: 535-541. (IF 5.385, Q1)

9Wei Gao*, Baoyong Sha*, Yongchun Liu, Daocheng Wu, Xin Shen, Guixia Jing. The effect of cationic starch on hemoglobin, and the primary attempt to encapsulate hemoglobin. Artificial Cells, Nanomedicine, and Biotechnology; 2015, 43(3):196-202. (IF 6.355, Q1)

10Wei Gao, YuzhuBian, Thomas M.S. Chang*. Novel Nanodimension artificial red blood cells that act as O2 and CO2 carrier with enhanced antioxidant activity: PLA-PEG nanoencapsulated PolySFHb-superoxide dismutase-catalase-carbonic anhydrase. Artificial Cells, Nanomedicine, and Biotechnology. 2013, 41(4): 232-239. (IF 6.355, Q1)

11Wei Gao, Baoyong Sha*, Yuan Zhao, Zhe Fan, Lin Liu & Xin Shen*. Comparison of simultaneous and sequential administration of fentanyl-propofol for surgical abortion: a randomized single-blinded controlled trial. Artificial Cells, Nanomedicine, and Biotechnology. 2017;45(5):1045-1050. (IF 6.355, Q1)

12Ying, Jun, Xiaobing Deng, Ruini Du, Qiyang Ding, Hao Tian, Yue Lin, Bin Zhou, Wei Gao*. Mitochondrial Modulation Treating Postoperative Cognitive Dysfunction Neuroprotection via DRP1 Inhibition by Mdivi1. Scientific Reports. 2024.14(1):26155. (IF 3.8, Q2)

13Wei Gao, Linzhong Zhang, Xuechang Han, Lai Wei, Jie Fang, Xiaqing Zhang, Jiaqiang Zhang, Haiyun Wang, Qi Zhou, Chenggang Wang, Wenting Chen, Xinli Ni, Lan Yang, Ruini Du, Ge Wang, Bingyu Liu, Yajuan Li, Shanshan Zhang and Qiang Wang*. Transcutaneous Electrical Acupoint Stimulation Decreases the Incidence of Postoperative Nausea and Vomiting After Laparoscopic Non-gastrointestinal Surgery: A Multi-Center Randomized Controlled Trial. Frontiers in Medicine. 2022, 09:(1-10). (IF 5.058, Q2)

14Yajuan Li, Bo Wang, Le Wang, Kewei Shi, Wangcheng Zhao, Sai Gao, Jiayu Chen, Chenguang Ding, Junkai Du* andWei Gao*. Postoperative day 1 serum cystatin C level predicts postoperative delayed graft function after kidney transplantation. Frontiers in Medicine, 2022, 9:863962. (IF 5.058, Q2)

15Keke Song, Rongrong Zhang, Xiaoqi Zhao, Lan Yang, Qiang Wang,Wei Gao*. Perioperative Neurocognitive Disorder Changes in Elderly Diabetes Patients within 30 Days after Surgery: A Retrospective Cohort Study. Aging Clinical and Experimental Research. 2023. 35(12):2911–18. (IF 3.4, Q3)

16Wang Le, Jin Huang, Yajuan Li, Kewei Shi, Sai Gao, Wangcheng Zhao, Shanshan Zhang, Chenguang Ding, Wei Gao*. Postoperative fasting plasma glucose and family history diabetes mellitus can predict post-transplantation diabetes mellitus in kidney transplant recipients. Endocrine. 2023 May 6. (IF 3.925, Q3)

17Keke Song, Tingting Yang,Wei Gao*. Association of hyperchloremia with all-cause mortality in patients admitted to the surgical intensive care unit: a retrospective cohort study. BMC Anesthesiology. 2022, 22(14), 2-8. (IF 2.376, Q3)

18Ning Bu, Enfa Zhao, Yuan Gao, Sha Zhao, Wang Bo, Zhidong Kong, Qiang Wang,Wei Gao*. Association between perioperative hypothermia and surgical site infection: a meta-analysis. Medicine, 2019;98(6), e14392. (IF 1.817, Q3)

19Wei Gao, Baoyong Sha*, Zhe Fan, Yansheng Liu, and Xin Shen*. Nanoformulation of premixing propofol lipid emulsion and fentanyl citrate and their effects on acute toxicity, sedation, and analgesia. Journal of Nanomaterials. 2016(4):1-8. (IF 3.791, Q3)

授权专利:

1高巍, 景桂霞, 徐礼鲜, 张惠.一种基于改性直链淀粉的纳米螺旋油相触发速释体及其制备方法,2013.2,中国,201310044338.2

2高巍,王强,朱宇麟,严军,一种亲水小分子靶向二级递送载药体及其制备方法,2017.2, 中国,201710115051.2

3高巍,宋珂珂,王强,闫超颖,王妮莎,夏季,张闪闪,一种缺血脑区靶向纳米线粒体及其制备方法、用途,2022.07,ZL 2022 1 0906755.2

4高巍,杜瑞妮,张烁,吴道澄,李燕,张闪闪,高媛, 一种氟化二氧化硅载药纳米粒及其制备方法、用途, 2022.07,ZL 2022 1 0906767.5

5高巍,卜宁,陈佳钰,王强,李岩松,张闪闪,高媛,一种乳铁蛋白阳离子淀粉球及其制备方法,2022.07.29, ZL 2022 1 0912182.4

获奖情况:

1高巍(1/1); 陕西省青年科技新星, 陕西省科技技术厅, 其他, 其他, 2018(高巍)

2高巍(1/1); 陕西省青年拔尖人才, 中共陕西省组织部, 其他, 其他, 2020(高巍)

3高巍(5/9); 中西医结合Ai-PCA减轻手术患者疼痛并加速康复的临床策略, 陕西省人民政府, 科技进步 省部二等奖

联系方式:

gaowei2906@xjtufh.edu.cn

友情链接:

通讯地址:陕西省西咸新区西咸大道陕西中医药大学研究生院招生办公室 邮政编码:712046

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